Correction: An Endophytic Fungus, Talaromyces radicus, Isolated from Catharanthus roseus, Produces Vincristine and Vinblastine, Which Induce Apoptotic Cell Death
نویسندگان
چکیده
Figs 9, 10, 14, 15 and 16 are incorrect. Although the legends are accurate, the final formatted version are not present. The authors have provided the corrected figures here. Fig 9. LC-ESI-MS analysis of fungal VCR. The mass spectrum of the fungal extract showed a (M+H+) peak at a molecular mass of 825.46, which was identical to that observed in the mass spectrum of the VCR standard. access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
An Endophytic Fungus, Talaromyces radicus, Isolated from Catharanthus roseus, Produces Vincristine and Vinblastine, Which Induce Apoptotic Cell Death
Endophytic fungi isolated from Catharanthus roseus were screened for the production of vincristine and vinblastine. Twenty-two endophytic fungi isolated from various tissues of C. roseus were characterized taxonomically by sequence analysis of the internal transcribed spacer (ITS) region of rDNA and grouped into 10 genera: Alternaria, Aspergillus, Chaetomium, Colletotrichum, Dothideomycetes, Eu...
متن کاملIsolation, Purification and Characterization of Vinblastine and Vincristine from Endophytic Fungus Fusarium oxysporum Isolated from Catharanthus roseus
Endophytic fungi reside in a symbiotic fashion inside their host plants, mimic their chemistry and interestingly, produce the same natural products as their hosts and are thus being screened for the production of valuable compounds like taxol, camptothecin, podophyllotoxin, etc. Vinblastine and vincristine are excellent anti-cancer drugs but their current production using plants is non-abundant...
متن کاملCultural, Morphological and Molecular Characterization of Vinca Alkaloids Producing Endophytic Fungus Fusarium Solani Isolated from Catharanthus Roseus
We have isolated fifty-two endophytic fungi (AA-CRL-1 to AA-CRL52) from the leaves of Catharanthus roseus plants collected from different parts of Pune (Maharashtra, India). These endophytic fungi represented different genera and were screened for vinca alkaloids production using TLC and ESI-MS analysis. Out of the 52 endophytic fungal cultures screened, the endophytic culture AA-CRL-20 was fou...
متن کاملFirst report on a novel Nigrospora sphaerica isolated from Catharanthus roseus plant with anticarcinogenic properties
This paper reports on the vinca alkaloid produced by a novel Nigrospora sphaerica isolated from Catharanthus roseus. Through liquid chromatography-mass spectrometry (LCMS), only the crude mycelia extract of this fungus was positive for determination of vinblastine. This vinca alkaloid was then purified by using high-performance liquid chromatography (HPLC) and tested for cytotoxicity activity u...
متن کاملFungal vincristine from Eutypella spp - CrP14 isolated from Catharanthus roseus induces apoptosis in human squamous carcinoma cell line -A431
BACKGROUND Catharanthus roseus, a medicinal plant, is known to produce secondary metabolites, vincristine and vinblastine, which are terpenoid indole alkaloids. Previously we have reported that Eutypella spp - CrP14 isolated from stem cutting of this plant had shown significant antiproliferative activity when tested in vitro against HeLa cell line. The present study was conducted to identify th...
متن کامل